Public APIs about Anti-Malware

IP/domain/URL reputation

IP/domain/URL reputation

Google Link/Domain Flagging

Provide malware datasets and threat intelligence feeds

Malware Archive / file sourcing

Collect and share malware samples

Metacert Link Flagging

IP/domain/URL reputation

Simple REST API that can scan submitted documents/files for the presence of threats

Bulk queries and Download Malware Samples

Scan and Analyse URLs

VirusTotal File/URL Analysis

IP/domain/URL reputation

Malware execution and analysis

Check links to see if they're known phishing attempts